Skip to main content

Bipolar and Related Disorders

Bipolar I Disorder

Bipolar I Disorder is diagnosed when there has been at least one manic episode. Mania is a distinct period of abnormally elevated, expansive, or irritable mood and increased energy or activity, with a significant change from usual functioning.

No history of major depression is required for diagnosis, although depressive episodes are common. Mania can cause severe functional impairment, hospitalisation or psychosis and requires prompt specialist care. Long-term treatment usually combines medication, psychoeducation, psychosocial support, and physical health monitoring.

What Is Bipolar I Disorder?

A manic episode lasts at least a week most of the day, almost every day, or for any duration if hospitalisation is necessary if hospitalisation is required. The mood is accompanied by persistently increased energy and specific symptoms. Severity is not judged by whether the person feels happy: mania may be primarily irritable, anxious or disorganized. There may be complete or partial remission between episodes, but there remains a need for relapse prevention.

Key Features and Signs of Mania

Symptoms appear along with a change in mood and energy and are a clear change from usual:

  • Excessively inflated self-esteem or grandiose beliefs.
  • Much less need for sleep, like a few hours without feeling tired.
  • Greater talkativeness than usual, pressured speech, or a feeling of pressure to keep talking.
  • Rapid flow of ideas or subjective feeling that thoughts are racing.
  • Intense distraction by irrelevant or trivial stimuli.
  • Large increase in goal-directed activity or purposeless psychomotor agitation.
  • Excessive involvement in high-risk activities such as spending, driving, investing, or sexual decisions.

How It Is Diagnosed

Diagnosis is based on a longitudinal history of mood, energy, sleep, and functioning. With the person's consent, information from people who know them well is often valuable because insight may be reduced during mania.

  • There is a distinct period of abnormally and persistently elevated, expansive, or irritable mood and abnormally increased activity or energy, present most of the day nearly every day for at least 1 week—or for any duration if hospitalisation is necessary.
  • At least 3 of 7 accompanying symptoms are required, or at least 4 when the mood is only irritable.
  • The change causes severe functional impairment, requires hospitalisation to prevent harm, or includes psychotic features.
  • The episode is not attributable to a substance, drug, or other medical condition and is not better explained by schizoaffective or other psychotic disorder.
  • For Bipolar I a manic episode is sufficient; major depressive episode is not diagnostically mandatory.
Clinical note: A full manic episode that emerges during antidepressant treatment but persists at a fully syndromal level beyond the physiological effect of that treatment can count as a manic episode. This requires specialist clinical assessment.

How It Can Affect Daily Life

In mania, high energy and confidence may initially seem productive, but judgement, sleep and personal safety may deteriorate. There may be debts, relationship breakdowns, job loss, accidents or legal consequences. Depressive episodes can be prolonged and severely impair functioning. The disorder does not define the person's personality or abilities and does not involve violence.

Causes and Risk Factors

Bipolar I is multifactorial, with a significant but complex genetic component and interaction of sleep, stress, developmental and social factors. Sleep deprivation, substances and certain medications can trigger an episode in vulnerable people, without being the sole cause. Family history increases risk at the population level but does not predict who will develop the disorder.

Similar or Co-occurring Conditions

The episodic change from the baseline functioning is central:

  • Bipolar II includes hypomania and major depression without mania. It is not an overall "mild" disorder, although hypomania is less severe than mania.
  • Attention-Deficit/Hyperactivity Disorder is a persistent neurodevelopmental pattern rather than a clear period of decreased need for sleep and mood swings.
  • Schizoaffective disorder and schizophrenia are assessed when psychosis occurs outside of mood episodes or dominates the overall course.
  • Substances, medications, hyperthyroidism, and other medical causes can mimic mania.
  • Borderline personality disorder may involve rapid emotional instability, but a different longitudinal and interpersonal pattern is assessed.

Treatment and Support

Treatment is differentiated for acute mania, bipolar depression and relapse prevention and requires special medical monitoring.

  • Acute mania is treated with appropriate medication and, when there is a serious risk, with hospitalisation in a safe environment.
  • Long-term treatment may include mood stabilizers or antipsychotics, with selection based on history, preferences, side effects, pregnancy, and physical health.
  • Psychoeducation, recognition of early signs, consistent sleep, and a relapse prevention plan enhance management.
  • Structured psychological and family interventions can support functioning, relationships, and adherence to treatment.
  • Monitoring of weight, metabolic markers, kidney, thyroid or other parameters is needed depending on the drug.
  • Do not abruptly stop treatment or use an antidepressant without a specific assessment of bipolar risk.

When to Seek Help

Seek immediate evaluation when the need for sleep is severely reduced, activity, speech, spending, or risky decisions increase rapidly, or psychosis occurs. Suicidal risk may be increased, particularly in depressive or mixed phases; current suicidal thoughts, plans, or attempts need immediate urgent evaluation.

Frequently Asked Questions

Do you need depression to be diagnosed with Bipolar I?

No. The diagnosis requires at least one manic episode. Major depressive episodes are common but not mandatory.

How many symptoms are needed for mania?

At least three of the seven accompanying symptoms are needed, or four when the mood is only irritable, along with increased energy, duration required, and severity.

Is Bipolar II just milder than Bipolar I?

No. Bipolar I mania is more severe than hypomania, but Bipolar II can cause severe and long-term burden due to depressive episodes.

Sources

  1. WHO: Bipolar disorder
  2. NICE CG185: Bipolar disorder
Call us +30 231 407 1153